The MATTERS Network began as a Buffalo, New York-based electronic referral platform to connect patients to medications for opioid use disorder (MOUDs). Buffalo MATTERs served to establish prescribing guidelines for physicians and advanced practice providers of opioid use disorder in Western New York. Our electronic referral platform efficiently refers patients with opioid use disorder from emergency departments, OB/GYN offices, correctional facilities, inpatient units, pre-hospital settings, etc. to community-based clinics.